Martin A. Smith is an Associate Professor at UNSW Sydney and Director of the Ramaciotti Centre for Genomics, Australia’s largest university-based genomics facility. He is a computational biologist specializing in genomics, transcriptomics, and epitranscriptomics, with a strong focus on long-read and nanopore sequencing technologies. He is a co-founder of RNAxis, developing RNA-based therapies to modulate T-cell biology.

His research integrates experimental and computational approaches to dissect RNA biology, genome architecture, and regulatory complexity, including long non-coding RNAs, RNA modifications, immune repertoires, and repetitive elements. Dr Smith has contributed widely used methods for native RNA sequencing, molecular barcoding, adaptive sampling, and machine learning–driven analysis of long-read data, with applications in oncology, infectious disease, and precision medicine. 

He has published extensively in leading journals including Cell, Nature Communications, and Nucleic Acids Research, and is an inventor on multiple patents licensed to industry, including Oxford Nanopore Technologies. At Multiomics 2026, he will discuss how single-molecule sequencing is reshaping integrative multiomic workflows from discovery to clinical deployment.